CathLabHub complications toolkitcathlabhub.com/toolkit/effusion-after-laao-teerIn review, October 24, 2026
Recognize
The signs on the monitor, the image and the patient.
- EchoA new or growing effusion on TEE or ICE during the case, or on the follow up echo 1.
- MonitorFalling pressure, a rising right atrial pressure and pulsus paradoxus 2.
- ImageA transseptal needle or sheath outside the fossa or at the appendage tip; contrast in the pericardium 1.
- PatientChest pain, dyspnea or hypotension hours to days later: late effusions occur after appendage closure 3.
Act now
In the order the operator does them. The first three come first, whatever else is happening.
- Stop advancing; keep wires and sheaths where they are until the source is clear.
- Echo the size and the hemodynamics; call the surgeon and anesthesia.
- Fluids and vasopressors while preparing 2.
- Drain now if there is any hemodynamic compromise; autotransfusion for brisk bleeding 24.
- Reverse heparin with protamine once no large device is in a vulnerable position 1.
- If the appendage is the source, completing the device deployment can seal it; decide with the surgeon.
- Ongoing bleeding despite drainage and reversal: surgery 12.
Equipment
From the complications cart. Linked items open in the equipment directory.
- Pericardiocentesis trayDirectory: Lock pericardiocentesis set and tray, Pericardiocentesis kit.
- Echo, TEE or ICENot in the directory yet.
- Venous sheath for autotransfusionDirectory: Pinnacle introducer sheath.
- Transseptal needle or radiofrequency wireDirectory: NRG transseptal needle, VersaCross RF transseptal solution.
Drugs
Adult doses as the cited source gives them. Check your formulary and the label.
- ProtamineTo reverse heparin.Weight based dose in the Cath Med App
- Norepinephrine0.1 to 0.5 mcg/kg/min IV 5.
Who to call
The escalation ladder, first call first.
- Echo: in the room.
- Cardiac surgery: at the event 1.
- Anesthesia: already present for TEE cases; tell them now.
- Second operator: to drain while you hold position.
The bailout step by step
Drain during a structural case 2
- Keep the TEE probe in; subcostal echo or fluoroscopy for the needle path.
- Subxiphoid 18 gauge sheathed needle with gentle aspiration 2.
- Confirm position with agitated saline or contrast; J wire, sheath, multihole pigtail 2.
- Aspirate to dryness; return blood through a venous sheath if bleeding is brisk 4.
- Reverse heparin; recheck the effusion on echo after a few minutes without drainage.
- Leave the drain until output is under 25 mL a day and echo shows no recurrence 2.
Prevent
- Know the size of the risk: serious pericardial effusion occurred in 4.8 percent of device patients in the early PROTECT AF trial 6.
- Imaging guided transseptal puncture in the right location for the procedure 3.
- Gentle sheath manipulation in the appendage, always over a pigtail or under imaging 3.
- Echo before the patient leaves the lab and before discharge 3.
After care and documentation
- Echo the next day and with any symptoms; late effusions occur 3.
- Document the source, the volume, reversal and drain removal.
- Report in the LAAO or TVT registry.
Practice
No emergency simulator case for this yet; the structural simulator in the app shows an effusion from the crossing or the sheath through its signs. Browse the case library.
References
- Holmes DR Jr, Nishimura R, Fountain R, Turi ZG. Iatrogenic pericardial effusion and tamponade in the percutaneous intracardiac intervention era. JACC Cardiovasc Interv 2009;2:705-717.
- Sorajja P. Pericardiocentesis. In: Kern MJ, ed. The Interventional Cardiac Catheterization Handbook. 3rd ed. Saunders, Elsevier; 2013. Chapter 18.
- Saw J, Holmes DR, Cavalcante JL, et al. SCAI/HRS expert consensus statement on transcatheter left atrial appendage closure. JSCAI 2023;2:100577.
- Brilakis ES. Manual of Percutaneous Coronary Interventions. Elsevier; 2021. Chapter 26, Perforation.
- Brilakis ES. Manual of Percutaneous Coronary Interventions: A Step-by-Step Approach. Academic Press, Elsevier; 2021. Chapter 3, Medications.
- Holmes DR, Reddy VY, Turi ZG, et al. Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial. Lancet 2009;374:534-542.
Educational reference for cath lab teams, not medical advice and not a standard of care. Your local policy, the device instructions for use and current guidelines govern. Verify every dose before use. Printed from cathlabhub.com/toolkit/effusion-after-laao-teer. First version, in clinical review: an interventional cardiologist is checking every card before it is final. Every number cites its source on the card.