CathLabHub complications toolkitcathlabhub.com/toolkit/atheroembolismIn review, October 24, 2026
Recognize
The signs on the monitor, the image and the patient.
- PatientLeg or foot pain, livedo reticularis and intact pulses: the classic triad 1.
- PatientBlue or purple toes, digital gangrene 2.
- LabEosinophilia and rising creatinine, often days to weeks later 12.
- PatientRetinal, gut or brain involvement in widespread embolization.
- LabIncidence 1.4 percent in a prospective study after cardiac catheterization 3.
Act now
In the order the operator does them. The first three come first, whatever else is happening.
- Recognize it and stop further aortic instrumentation where possible.
- Supportive care for the kidney, the skin and the limb 1.
- Statins may help the kidney injury 1.
- Pain control and wound care for the toes.
- Nephrology for renal failure; dialysis when needed.
- Sources differ: Kern reports in hospital mortality up to 16 percent in definite cholesterol embolization syndrome; outcomes vary with the extent 2.
Equipment
From the complications cart. Linked items open in the equipment directory.
- J tipped wire to lead catheters in the aortaDirectory: Starter guidewire.
- Radial sheathsDirectory: Glidesheath Slender.
Drugs
Adult doses as the cited source gives them. Check your formulary and the label.
- StatinMay help the kidney injury 1.
Who to call
The escalation ladder, first call first.
- Nephrology: for the kidney.
- Vascular surgery or wound care: for digital ischemia.
- Dermatology: if the diagnosis needs a skin biopsy.
The bailout step by step
Catheter technique that lowers the embolic load 2
- Lead every catheter with a wire through the aorta 2.
- Aspirate blood from the catheter after it reaches the root and discard it before injecting 2.
- Clear the Y connector before advancing through it 2.
- Use the fewest catheter exchanges and the smallest catheters that will do.
- Choose the access that avoids the most diseased aorta.
Prevent
- Wire led catheter advancement and aspiration of debris 2.
- Radial access in a diseased abdominal aorta.
- Fewer exchanges in a shaggy aorta.
After care and documentation
- Follow creatinine and skin findings for weeks.
- Document the findings and the eosinophil count.
Practice
No emergency simulator case for atheroembolism. Browse the case library.
References
- Brilakis ES. Manual of Percutaneous Coronary Interventions. Elsevier; 2021. Chapter 29, Vascular access complications.
- Berg R, Lim MJ. Complications of percutaneous coronary interventions. In: Kern MJ, ed. The Interventional Cardiac Catheterization Handbook. 3rd ed. Saunders, Elsevier; 2013. Chapter 4.
- Fukumoto Y, Tsutsui H, Tsuchihashi M, et al. The incidence and risk factors of cholesterol embolization syndrome, a complication of cardiac catheterization: a prospective study. J Am Coll Cardiol 2003;42:211-216.
Educational reference for cath lab teams, not medical advice and not a standard of care. Your local policy, the device instructions for use and current guidelines govern. Verify every dose before use. Printed from cathlabhub.com/toolkit/atheroembolism. First version, in clinical review: an interventional cardiologist is checking every card before it is final. Every number cites its source on the card.